Issue 2/2019 – Editorial

Dear Readers, Authors, Reviewers and Editorial Board Members of the Journal of Gerontology and Geriatrics, I am delighted to introduce you the 2nd Issue of the 2019 Volume, which includes 9 interesting contributions. As you will notice from the selected manuscripts, the Journal has definitely caught up the attention of an International authorship and readership.

We open with an Original Investigation by Y. Tozawa, who proposes intriguing working hypotheses on a common mechanistic theory of aging, starting from his observation on the age-related increase in indole-2,3-dione and its derivatives. The Author argues that this compound interferes with several enzymatic systems, whose failure leads to cell senescence. The second Original Investigation by D. Lelli et al. is a metanalysis on the effectiveness of telemonitoring in reducing hospitalization in older subjects with heart failure. The third Original Investigation by I. Rashid et al. is an epidemiological study on the frequency and risk factors associated with falls in aged patients hospitalized in a tertiary care public teaching hospital in India. In the fourth Original Investigation, R.S. Hosseini et al. tested the validity and reliability of the self-rated health, a tool for evaluating health status, in Iranian community-dwelling older adults. The fifth Original Investigation by C.S. Tan et al. described the prevalence of dental problems in aged patients of a hospital in Brunei.

The Issue also includes four stimulating Reviews. The first one by D. Nilaweera et al. consider the mechanisms by which stressful or traumatic events could be determinant in the development of dementia. In the second Review, T. Ciarambino et al. focus on gender differences in the effectiveness and safety of direct oral anticoagulants in the elderly. In the third contribution, P. Canepa reviews the current literature on the possible association between the purple urine bag syndrome – a condition characterized by the urinary presence of tryptophan produced by intestinal bacteria, such as E. coli – and Alzheimer’s disease. The fourth Review by M. Mollica et al. considers the management of lung cancer in the elderly, pointing out the poor available data from clinical trials on aged patients.

To conclude, I hope that you will enjoy reading (and citing!) the contributions of this JGG issue, and I kindly remind you that we continue to welcome your submissions to the Journal. Also, should you have any suggestions or comments, please feel always free to contact us.

Gianluigi Vendemiale

Editor-in-Chief

Journal of Gerontology and Geriatrics