TY - JOUR AU - Silecchia, G. AU - selvaggio, O. AU - Berret, E. AU - Sanguedolce, F. AU - Stallone, G. AU - Cormio, L. PY - 2018/12/15 Y2 - 2024/03/28 TI - A lycopene and olives vegetation water compound improves lower urinary tract symptoms in men with histologically-proven benign prostatic hyperplasia and inflammation JF - JOURNAL OF GERONTOLOGY AND GERIATRICS JA - Gerontology and Geriatrics VL - 66 IS - 4 SE - Clinical Geriatrics - Short Communications DO - UR - https://www.jgerontology-geriatrics.com/article/view/73 SP - 211-215 AB - Background and aims. There is evidence for the ability of antioxidants to counteract the effects of inflammation. We aimed to determine whether the administration of a lycopene/olives vegetation water compound might reduce prostatic inflammation and consequent lower urinary tract symptoms in patients with histologically proven prostatic inflammation.Methods. Over a month period, patients having undergone prostate biopsy and having been diagnosed withbenign prostate were given lycopene/olives vegetarian water compound (Group A). Data were compared withthose of a matched population of patients who did not receive such treatment (Group B). International prostatesymptom score, peak flow rate and post-void residual were recorded before and at the end of treatment.Results. The 17 patients in group A and the 17 in group B, had similar age, PSA, prostate volume, peak flowrate and post-void residual, but patients in Group A had lower median international prostate symptoms scorethan those in group B (7 vs 12; p = 0.012). All patients in group A successfully completed treatment with no sideeffect. Group B experienced no difference in international prostate symptoms score, peak flow rate and postvoid residual whereas group A experienced no difference in peak flow rate, a slight reduction in post-void residual and a decrease in international prostate symptoms score. Most important, reduction in international prostate symptoms score was significantly higher in group A than in group B (-2.0 vs 0, respectively; p = 0.0004).Conclusions. The lycopene/olives vegetation water compound seems to be effective in counteracting lowerurinary tract symptoms due to prostatic inflammation. ER -