@article{Oscanoa Espinoza_Amado-Tineo_Ayala-García_Mamani-Quiroz_Matta-Pérez_Ardiles-Melgarejo_Marcos-Hernández_Taype-Huamaní_Rojas-Guimaray_Matos-Santiváñez_Miranda-Chávez_Deza-Sime_Apolaya-Segura_Romero-Ortuno_2022, title={Clinical features and mortality predictors of older hospitalized patients with severe COVID-19 in Lima, Peru}, volume={71}, url={https://www.jgerontology-geriatrics.com/article/view/470}, DOI={10.36150/2499-6564-N470}, abstractNote={<p><strong>Background and aims.</strong> The objective of our study was to describe the clinical features of severe COVID-19 in older (compared to younger) hospitalized patients in a tertiary care centre in Lima, Peru. <br><strong>Methods</strong>. A retrospective observational study was conducted that included patients hospitalized for severe COVID-19 between March and May 2020. The clinical features of the older group (age ≥ 60 years) were compared with those of younger patients (age &lt; 60 years). A classification and regression tree (CRT) was computed to evaluate and visualize the main predictors of mortality in the total sample. <br><strong>Results</strong>. The study included 339 patients, 213 in the older and 126 in the younger group. Mortality was higher in the older group, 76.5 <em>vs</em> 42.1% (p &lt; 0.001). Within the older group, factors associated with higher mortality were older age (p = 0.006), hypertension (p = 0.039) and obesity (p = 0.034). The older group had higher D-Dimer (p = 0.044), C-reactive protein (CRP) (p = 0.031) and total bilirubin (p = 0.007); and lower lymphocyte count (p = 0.003), albumin (p &lt; 0.001) and Alanine aminotransferase (ALT) (p = 0.003). In the older group, CRT showed that the best predictor of mortality was the chest Computed Tomography Total Severity Score, with those with a score over 12 having 85.2% mortality. <br><strong>Conclusions</strong>. Mortality in patients hospitalized with severe COVID-19 was high, especially in older patients. In the latter, mortality was best predicted by an objective radiological marker of chest disease.</p&gt;}, number={2}, journal={JOURNAL OF GERONTOLOGY AND GERIATRICS}, author={Oscanoa Espinoza, Teodoro J. and Amado-Tineo, José and Ayala-García, Ricardo and Mamani-Quiroz, Roxana and Matta-Pérez, Javier and Ardiles-Melgarejo, Ángel and Marcos-Hernández, Carlos and Taype-Huamaní, Waldo and Rojas-Guimaray, Jefferson and Matos-Santiváñez, Sthephany and Miranda-Chávez, Loyda and Deza-Sime, Ana and Apolaya-Segura, Moisés and Romero-Ortuno, Roman}, year={2022}, month={Dec.}, pages={37-46} }