@article{Castagna_Coppolino_Leonardi_Cerra_Greco_Battaglia_Ruberto_Ruotolo_2019, title={Fahr’s disease: follow-up of a clinical case with severe cognitive impairment in absence of extrapyramidal disorders}, volume={67}, url={https://www.jgerontology-geriatrics.com/article/view/37}, abstractNote={<p>Fahr’s disease (FD), also known as familial idiopathic basal ganglia calcification, is a neurodegenerative disease<br>affecting cerebral microvessels, mainly in the basal ganglia. It mostly presents with movement disorders,<br>dementia and behavioural abnormalities. It is considered hereditary with an autosomal dominant transmission.<br>Fahr’s disease is often underestimated and underdiagnosed. We describe a rare case of Fahr’s disease: it<br>manifested itself with cognitive and behavioural alterations in absence of extrapyramidal disorders. Diagnosis<br>was supposed only after CT scan. Since onset of FD may only present with cognitive dysfunction without extrapyramidal<br>signs, physicians should consider this complex syndrome when consulting patients with mental<br>deterioration and behavioral abnormalities. Neurological and psychological examinations and CT imaging remain<br>the basic techniques for the diagnosis of Fahr’s disease.</p&gt;}, number={4}, journal={JOURNAL OF GERONTOLOGY AND GERIATRICS}, author={Castagna, A. and Coppolino, G. and Leonardi, G. and Cerra, R.P. and Greco, L. and Battaglia, G.G. and Ruberto, C. and Ruotolo, G.}, year={2019}, month={Dec.}, pages={290-293} }