@article{Serafini_Marzetti_Calvani_Picca_Tosato_Bernabei_Landi_2019, title={Nutritional approach to sarcopenia}, volume={67}, url={https://www.jgerontology-geriatrics.com/article/view/107}, abstractNote={<p>To maintain a good balance of skeletal muscle mass, it is important to consume high amount of proteins and<br>specific amino acids. In fact, the main nutritional stimulus for protein synthesis is represented by amino acids<br>derived from food protein; in particular, leucine is the main dietary regulator of muscle protein anabolism. It is<br>also important to select the quality of proteins taken up with the diet. Proteins show specific absorption rates<br>based on amino acid composition and are distinguished into “fast” or “slow” absorption proteins. Research has<br>shown that proteins, essential amino acids, leucine, hydroxymethylbutyrate (HMB) and vitamin D play a role<br>in the metabolism of skeletal muscle and are valid nutritional supplements. Being sarcopenia a complex geriatric&nbsp;syndrome, the most effective approach for its prevention and management is represented by multimodal&nbsp;interventions that mainly include physical exercise and nutritional intervention. The important role of nutrition&nbsp;in both prevention and management of sarcopenia is proven by the remarkable evidence linking nutrition with&nbsp;muscle mass and function. Therefore, the best strategy to prevent and treat sarcopenia in older people is to&nbsp;combine a specific exercise protocol and adequate amino acid intake, as expected in the multi-center European&nbsp;clinical trail “Sarcopenia and Physics fRailty IN elderly: multi-component treatment strategies” (SPRINTT).</p&gt;}, number={01 Special}, journal={JOURNAL OF GERONTOLOGY AND GERIATRICS}, author={Serafini, E. and Marzetti, E. and Calvani, R. and Picca, A. and Tosato, M. and Bernabei, R. and Landi, F.}, year={2019}, month={Mar.}, pages={52-61} }