Special Issue (September 2019)
Cardiac visceral fat and age-related cardiovascular diseases
Guest Editor: Prof. Dario Leosco – Università di Napoli “Federico II”, Italy
Deadline submission: 31.07.2019
Epicardial adipose tissue (EAT) is the visceral fat depot of the heart which covers 80% of the heart’s surface.
This fat is metabolically active and is able to directly interact with cardiomyocytes and to influence the myocardium and epicardial coronary arteries through paracrine and vasocrine signaling.
EAT functions as a source of free fatty acids and of bioactive molecules that, in physiological conditions, play a protective and favorable action for the heart.
However, in pathological conditions, EAT amount and its secretory properties are altered with high production of pro-inflammatory and pro-atherogenic cytokines.
The special issue of Journal of Gerontology and Geriatrics will focus on the implications of cardiac visceral fat in the pathogenesis of cardiovascular diseases in the elderly.