Short Communication
Published: 2018-12-15

lycopene and olives vegetation water compound improves lower urinary tract symptoms in men with histologically-proven benign prostatic hyperplasia and inflammation

Urology and Renal Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, Italy
Urology and Renal Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, Italy
Department of Urology, Institut Montsouris, Paris, France
Section of Pathology; Department of Clinical and Experimental Medicine, University of Foggia, Italy
Nephrology, Dialysis and Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, Italy
Urology and Renal Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, Italy
Lycopene Olives vegetation water Prostatic inflammation LUTS Benign prostatic Hyperplasia

Abstract

Background and aims. There is evidence for the ability of antioxidants to counteract the effects of inflammation.
We aimed to determine whether the administration of a lycopene/olives vegetation water compound
might reduce prostatic inflammation and consequent lower urinary tract symptoms in patients with histologically
proven prostatic inflammation.
Methods. Over a month period, patients having undergone prostate biopsy and having been diagnosed with
benign prostate were given lycopene/olives vegetarian water compound (Group A). Data were compared with
those of a matched population of patients who did not receive such treatment (Group B). International prostate
symptom score, peak flow rate and post-void residual were recorded before and at the end of treatment.
Results. The 17 patients in group A and the 17 in group B, had similar age, PSA, prostate volume, peak flow
rate and post-void residual, but patients in Group A had lower median international prostate symptoms score
than those in group B (7 vs 12; p = 0.012). All patients in group A successfully completed treatment with no side
effect. Group B experienced no difference in international prostate symptoms score, peak flow rate and postvoid
residual whereas group A experienced no difference in peak flow rate, a slight reduction in post-void residual
and a decrease in international prostate symptoms score. Most important, reduction in international prostate
symptoms score was significantly higher in group A than in group B (-2.0 vs 0, respectively; p = 0.0004).
Conclusions. The lycopene/olives vegetation water compound seems to be effective in counteracting lower
urinary tract symptoms due to prostatic inflammation.

Affiliations

G. Silecchia

Urology and Renal Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, Italy

O. selvaggio

Urology and Renal Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, Italy

E. Berret

Department of Urology, Institut Montsouris, Paris, France

F. Sanguedolce

Section of Pathology; Department of Clinical and Experimental Medicine, University of Foggia, Italy

G. Stallone

Nephrology, Dialysis and Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, Italy

L. Cormio

Urology and Renal Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, Italy

Copyright

© Società Italiana di Gerontologia e Geriatria (SIGG) , 2018

How to Cite

[1]
Silecchia, G., selvaggio, O., Berret, E., Sanguedolce, F., Stallone, G. and Cormio, L. 2018. lycopene and olives vegetation water compound improves lower urinary tract symptoms in men with histologically-proven benign prostatic hyperplasia and inflammation. JOURNAL OF GERONTOLOGY AND GERIATRICS. 66, 4 (Dec. 2018), 211-215.
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