Review
Published: 2017-03-15

Recent advances in basic and clinical research on the prevention and treatment of the metabolic syndrome and related disorders by the use of olive polyphenols

School for Specialists in Clinical Biochemistry, Department of Biomedical Experimental and Clinical Sciences, University of Florence, Italy
Department of Biomedical Experimental and Clinical Sciences, University of Florence, Italy
Oleuropein Olive leaf extract Olive tree polyphenols Metabolic syndrome Age-related dysmetabolism Type 2 diabetes

Abstract

Type 2 diabetes mellitus (T2DM) has been defined, together with obesity, the XXI century epidemic and, together
with cardiovascular disease, concurs to define a pathological condition known as metabolic syndrome.
T2DM can be prevented by an adequate lifestyle and treated, in the preclinical stage and at the onset of the
clinical signs, by a diet rich in olive tree polyphenols, in addition to the pharmacological therapy. Studies on
animals and humans suggest that olive tree and other plant polyphenols contribute significantly to most of the
beneficial effects associated with the Mediterranean diet including reduced cardiovascular disease, T2DM,
cancer and aging-associated neurodegeneration. These studies suggest the possible use of plant polyphenols
in dietary supplements as nutraceuticals useful against the metabolic syndrome and related conditions, particularly
T2DM. The present review summarizes the scientific data on the healthy virtues of the olive polyphenols
that support such conclusion.

Affiliations

G. Liguri

School for Specialists in Clinical Biochemistry, Department of Biomedical Experimental and Clinical Sciences, University of Florence, Italy

M. Stefani

Department of Biomedical Experimental and Clinical Sciences, University of Florence, Italy

Copyright

© Società Italiana di Gerontologia e Geriatria (SIGG) , 2017

How to Cite

[1]
Liguri, G. and Stefani, M. 2017. Recent advances in basic and clinical research on the prevention and treatment of the metabolic syndrome and related disorders by the use of olive polyphenols. JOURNAL OF GERONTOLOGY AND GERIATRICS. 65, 1 (Mar. 2017), 48-58.
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