Review
Published: 2017-03-15

Aging and cardiac autonomic control in chronic heart failure: methods and clinical implications

"S. Maugeri” Foundation, Scientific Institute of Telese Terme (BN), IRCCS Telese Terme, Italy
Department of Medicine and Health Sciences “V. Tiberio”, University of Molise, Campobasso, Italy
DIETI, University of Naples, “Federico II”, Naples, Italy
“S. Maugeri” Foundation, Scientific Institute of Telese Terme (BN), IRCCS Telese Terme, Italy
“S. Maugeri” Foundation, Scientific Institute of Telese Terme (BN), IRCCS Telese Terme, Italy
“S. Maugeri” Foundation, Scientific Institute of Telese Terme (BN), IRCCS Telese Terme, Italy; Department of Translational Medical Sciences, University of Naples “Federico II” Naples, Italy
HRV Poincarè analysis Fractal analysis

Abstract

A large body of evidence has been provided that cardiac autonomic control is deranged in heart failure. It is
also commonly accepted that aging is characterized by several molecular and structural changes in organs
and tissues, and per se affects cardiac autonomic control. Hence, as far as we are concerned with heart failure
in the elderly, both cardiac diseases and age are likely to contribute to the autonomic dysfunction of these
patients.
In the first part a brief review to the methods currently used to assess the autonomic control of the cardiovascular
function in human subjects is reported. Then, major findings on the relationship between aging and
cardiac autonomic indexes in normal subjects are presented. In the third part, main concept and experimental
observations on autonomic dysfunction in heart failure are reviewed. Finally, some basic considerations on the
relationship between aging, cardiac autonomic function and heart failure are introduced.
1. A brief review to the methods currently used to assess the autonomic control of the cardiovascular function
in human subjects is reported.
2. The relationship between aging and cardiac autonomic indexes in normal subjects are presented.
3. Main concept and experimental observations on autonomic dysfunction in heart failure are reviewed.

Affiliations

G. D'Addio

"S. Maugeri” Foundation, Scientific Institute of Telese Terme (BN), IRCCS Telese Terme, Italy

G. Corbi

Department of Medicine and Health Sciences “V. Tiberio”, University of Molise, Campobasso, Italy

M. Cesarelli

DIETI, University of Naples, “Federico II”, Naples, Italy

G. Rengo

“S. Maugeri” Foundation, Scientific Institute of Telese Terme (BN), IRCCS Telese Terme, Italy

G. Furgi

“S. Maugeri” Foundation, Scientific Institute of Telese Terme (BN), IRCCS Telese Terme, Italy

N. Ferrara

“S. Maugeri” Foundation, Scientific Institute of Telese Terme (BN), IRCCS Telese Terme, Italy; Department of Translational Medical Sciences, University of Naples “Federico II” Naples, Italy

Copyright

© Società Italiana di Gerontologia e Geriatria (SIGG) , 2017

How to Cite

[1]
D’Addio, G., Corbi, G., Cesarelli, M., Rengo, G., Furgi, G. and Ferrara, N. 2017. Aging and cardiac autonomic control in chronic heart failure: methods and clinical implications. JOURNAL OF GERONTOLOGY AND GERIATRICS. 65, 1 (Mar. 2017), 38-47.
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