Role of age in prostate and bladder cancer. A critical overview

F. Sanguedolce 1, M. Chirico 2, G. Stallone 3, L. Cindolo 4, A. Tewari 5, G. Carrieri 2

1 Section of Pathology, Department of Clinical and Experimental Medicine, University of Foggia, Italy; 2 Urology and Renal Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, Italy; 3 Nephrology, Dialysis and Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, Italy; 4 Department of Urology, ASL02 Abruzzo, ‘S. Pio da Pietrelcina’ Hospital, Vasto, Italy; 5 Department of Urology, Mount Sinai School of Medicine, New York, USA

Age has been suggested to be a relevant prognostic factor in several diseases. According to the latest statistics, prostate and bladder cancer are among the most frequent urogenital tumors and their incidence increases with age. Available data suggest that age may drive the diagnostic and therapeutic pathways of both prostate and bladder cancer. Contrary to common perception, age seems to have a negative prognostic impact on many aspects of such cancers. Age per se does not seem to represent a contraindication to actively search for and treat such cancers but it would rather be a factor to be taken in due account in the decision-making process. 

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