High fish consumption decreased the likelihood of depressive symptoms in community-living older people: a randomized-controlled trial

A. Shapouri-Moghaddam 1, M. Bagherniya 2, S.-M. Ehteshamfar 3, H. Rahimi 4, M. Safarian 2

1 Department of Immunology, Avicenna Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran; 2 Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; 3 Department of Immunology, Immunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; 4 Department of Modern Sciences & Technologies, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Background and aims. This study was an attempt to examine the interventional relationship between regular fish consumption and depression among the elderly, Mashhad, Iran.

Methods. A total of 96 adults who aged 60 years or over was recruited and then divided into groups A and B. The subjects’ initial eligibility was tested using Beck Depression Inventory (BDI). Group A received fish four times a week whereas their peers in group B consumed fish two or fewer times per week. The outcome measures were 12-item general health questionnaire (GHQ-12) and 15-item Geriatric Depression scale (GDS-15).

Results. The results indicated that GHQ and GDS scores decreased non-considerably following three-month intervention. Fish consumption was associated with a lower likelihood of depression (dichotomized GDS: OR[odds ratio] = 0.73, 95% CI[confidence interval] = 0.28-1.87, p = 0.618; dichotomized GHQ: OR = 0.67, 95% CI = 0.26-1.73; p = 0.334).

Conclusions. It could be concluded that diet supplementation of the elderly with fish decreased the likelihood of depressive symptoms. However, this improvement was not statistically significant.

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